Mechanisms and Evolution of Intergenerational Change

Artistic representation of the evolutionary tree of life
24 September, 2019 - 26 September, 2019

Wellcome Genome Campus, Hinxton, Cambridge, CB10 1RQ


Click here to register

General Information

Recent observations strongly suggest that changes in maternal stress signalling can lead to altered development in offspring and changes in offspring physiology across evolutionary lineages. In mammals, studies suggest that maternal exposure to environmental stress during pregnancy can lead to an increased risk of a variety of pathologies in later life including diabetes, cardiovascular disease, depression and anxiety. This new conference will compare and contrast mechanisms of intergenerational change in diverse organisms, to help us understand how the maternal environment contributes to developmental programming and disease susceptibility.

The programme places particular emphasis on comparing mechanisms underlying maternal effects observed throughout ecology and evolution with the mechanisms underlying foetal programming in mammals. The overall aim is to explore whether the developmental origins of health and disease are caused by conserved molecular mechanisms and if they can be prevented or reversed.

The conference will bring together scientists working on foetal programming and developmental origins of health and disease in humans and animals (with a focus on the mechanisms underlying the developmental programming) with ecologists and evolutionary biologists interested in the effects of the parental environment on offspring physiology.
We welcome abstracts on all major themes of this meeting for oral or poster presentations.

For more information see the event website here.

Registration and abstract submission here, registration deadline 6th August, deadline for abstract submissions 2nd July.


Keynote speakers

Pat Monaghan – University of Glasgow, UK
Kent Thornburg – University of Oregon, USA

Confirmed speakers

Tracy Bale – University of Maryland, USA
Ryan Baugh – Duke University, USA
Kathleen Donohue – Duke University, USA
Anne Ferguson-Smith – University of Cambridge, UK
Dino Giussani – University of Cambridge, UK
Bram Kuijper – University of Exeter, UK
Cris Ledón-Rettig – Indiana University, USA
Kirsty MacLeod – University of Lund, Sweden
Susan Ozanne – University of Cambridge,UK
Andrew Pospisilik – Max Planck Institute of Immunobiology and Epigenetics, Germany
Tessa Roseboom – University of Amsterdam, The Netherlands
Karen Spencer – University of St. Andrews, UK
Tobias Uller – University of Lund, Sweden
Jurriaan Ton – University of Sheffield, UK