Science programme – gene regulation, chromatin, epigentics

Registration will open for the meeting at 09:30 and coffee will be available until 10:00


Gene Regulation, Chromatin, Epigenetics


Dr Terri Grodzicker (Cold Spring Harbor Laboratory, USA)

Thursday 8 November 2012


10:00 – 10:15 Terri Grodzicker (Cold Spring Harbour Laboratory, USA)

Welcome to the Genetics Society’s Autumn Meeting

10:15 – 10:55 Dr Bruce Stillman (Cold Spring Harbour Laboratory,USA)

The Origin Recognition Complex: Chromosome Duplication and Separation

10:55 – 11:35 Dr Sharon Dent (MD Anderson Cancer Centre, USA)

New Functions for Histone Modifying Enzymes

11:35 – 12:15 Dr Stephen Smale (David Geffen School of Medicine,UCLA, USA)

Transcript dynamics of proinflammatory genes revealed by RNA-seq analysis of subcellular RNA fractions

12:15 – 12:55 Dr Jerry Workman (Stowers Institute for Medical Research, USA)

Chromatin reassembly following RNA polymerase II transcription

13:00 – 14:00 Lunch


DNA Replication, Repair, Checkpoints, Chromosomes


Professor Winship Herr (Universite de Lausanne, Switzerland)

Thursday 8 November 2012


14:00 – 14:40 Professor Winship Herr (Universite de Lausanne, Switzerland)

14:40 – 15:20 Dr Steve Elledge (Harvard Medical School, USA)

Genetic Mining of the Cancer Genome

15:20 – 15:40 Coffee

15:40 – 16:20 Professor Steve Jackson (Wellcome Trust/Cancer Research UK Gurdon Institute, UK)

The DNA-damage response: molecular insights and new approaches to cancer therapy


The President of the Genetics Society, Professor Enrico Coen


16:20 – 17:30 Steve West (London Research Institute, UK)

DNA strand break repair, genome instability and cancer

The 2012 Genetics Society Medal

17:30 – 18:30 Wine Reception




Professor Rudi Grosschedl (Max-Planck Institute of Immunobiology & Epigenetics, Germany)

Friday 9 November 2012


09:00 – 09:40 Dr Susan Gottesman (Centre for Cancer Research, USA)

Coordinating the response to stress with bacterial small RNAs

09:40 – 10:20 Professor Narry Kim (Seoul National University, Korea)

Biogenesis and regulation of microRNA

10:20 – 10:50 Coffee

10:50 – 11:30 Dr Elisa Izarralde (Max-Planck Institute for Developmental Biology, Germany)

Regulation of mRNA expression by miRNAs and RNA-binding proteins

11:30 – 12:10 Dr Jim Manley (University of Columbia, USA)

RNA Processing: Mechanisms and links to other cellular processes

12:10 – 12:50 Professor Joan Steitz (Yale University, USA)

Noncoding RNAs: with a viral twist

13:00 – 14:00 Lunch


Stem Cells, Cancer and Development


Dr Davor Solter (Institute of Medical Biology, Singapore)

Friday 9 November 2012


14:00 – 14:40 Dr Eileen White (The Cancer Institute of New Jersey, USA)

Role of autophagy in lung cancer

14:40 – 15:20 Professor Hans Clevers (Hubrecht Institute, The Netherlands)

Wnt signaling, Lgr5 stem cells and cancer

15:20 – 16:00 Professor Elaine Fuchs (The Rockefeller University, USA)

Skin stem cells: in homeostasis, wound-repair and cancer

16:00 – 16:30 Coffee

16:30 – 17:10 Dr Ken Zaret (University of Pennsylvania, USA)

Programming and Reprogramming Cell Fate

17:10 – 17:50 Professor Nick Hastie (MRC Institute of Genetics & Molecular Medicine, UK)

WT1 and Mesenchyme in Cancer, Development and Adult Tissue Homeostasis

17:50 – 18:30 Professor Rich Losick (Harvard University, USA)

Cell fate switching in a bacterium

18:30 Close of Genetics Society Autumn 2012 Meeting